Adamantinoma

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Adamantinoma

Introduction

    Rare low-grade malignant tumor of unknown etiology that is almost always located in the mid-tibia

  • Epidemiology
  • incidence
  • less than 300 cases have been documented
  • demographics
  • occurs in young adults (20 - 40 years of age)
  • Associated conditions
  • osteofibrous dysplasia

    Historically, it was thought that osteofibrous dysplasia (OFD) was a precursor to this adamantinoma, however current studies have cast doubt on this theory

  • Prognosis
  • may metastasize to lungs (25%), therefore long-term follow-up is recommended
  • recurrence is uncommon with negative margin excision

Treatment

    Operative

  • wide-margin surgical resection 
  • indications
  • standard of care in most patients
  • techniques
  • often requires intercallary resection with allograft or intercallary megaprosthesis reconstruction as adamantinoma is a low-grade malignancy, radiotherapy and/or chemotherapy is not typically used for local control of disease

Differentials & Treatment Groups

  • Osteofibrous dysplasia
  • differentiating between osteofibrous dysplasia and adamantinoma is critical
  • osteofibrous dysplasia is benign and  treated with observation
  • adamantinoma is malignant and treat with surgical resection

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Journal Considers Research article, Review articles, editorial, letter, case reports, short communications, original articles from leading scientists and scholars around the world in all areas of related to Malignantosteoid, Multilobular tumour of bone, Chondrosarcoma, Chordoma, Osteosarcoma, Ewing's sarcomaetc., which come under the scope of the journal.

 

 

Feb 06, 2021

Author

Stella

Category