Overview

Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the bone marrow — the spongy tissue inside bones where blood cells are made. CML causes an increased number of white blood cells in the blood.

The term "chronic" in chronic myelogenous leukemia indicates that this cancer tends to progress more slowly than acute forms of leukemia. The term "myelogenous" (my-uh-LOHJ-uh-nus) in chronic myelogenous leukemia refers to the type of cells affected by this cancer.

Chronic myelogenous leukemia can also be called chronic myeloid leukemia and chronic granulocytic leukemia. It typically affects older adults and rarely occurs in children, though it can occur at any age.

Advances in treatment have contributed to a greatly improved prognosis for people with chronic myelogenous leukemia. Most people will achieve remission and live for many years after diagnosis.

Symptoms

Chronic myelogenous leukemia often doesn't cause signs and symptoms. It might be detected during a blood test.

When they occur, signs and symptoms may include:

Bone pain

Easy bleeding

Feeling full after eating a small amount of food

Feeling run-down or tired

Fever

Weight loss without trying

Loss of appetite

Pain or fullness below the ribs on the left side

Excessive sweating during sleep (night sweats)

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