Steric effects

Journal of Ecosystem and Ecography  is an international open access journal publishing the quality peer-reviewed research articles relevant to the field of Environmental Sciences. The journal selects the articles to be published with a single bind, peer review system, following the practices of good scholarly journals. It supports the open access policy of making scientific research accessible to one and all.

Journal Impact Factor 0.02^*; 1.5^* (5 Year Journal Impact Factor)
Submit manuscript at https://www.scholarscentral.org/submissions/ecosystem-ecography.html 

Steric effects are nonbonding interactions that influence the shape (conformation) and reactivity of ions and molecules. Steric effects complement electronic effects, which dictate the shape and reactivity of molecules. Steric repulsive forces between overlapping electron clouds result in structured groupings of molecules stabilized by the way that opposites attract and like charges repel.

Steric hindrance is a consequence of steric effects. Steric hindrance is the slowing of chemical reactions due to steric bulk. It is usually manifested in intermolecular reactions, whereas discussion of steric effects often focus on intramolecular interactions. Steric hindrance is often exploited to control selectivity, such as slowing unwanted side-reactions.

Steric hindrance between adjacent groups can also affect torsional bond angles. Steric hindrance is responsible for the observed shape of rotaxanes and the low rates of racemization of 2,2'-disubstituted biphenyl and binaphthyl derivatives.

Measures of steric properties

Because steric effects have profound impact on properties, the steric properties of substituents have been assessed by numerous methods.

Rate data

Relative rates of chemical reactions provide useful insights into the effects of the steric bulk of substituents. Under standard conditions methyl bromide solvolyzes 107 faster than does neopentyl bromide. The difference reflects the inhibition of attack on the compound with the sterically bulky (CH₃)₃C group.

A-values

A values provide another measure of the bulk of substituents. A values are derived from equilibrium measurements of monosubstituted cyclohexanes. The extent that a substituent favors the equatorial position gives a measure of its bulk.

Editorial Manager® System is an online submission and review system, where authors can submit manuscripts and track their progress. Reviewers can download manuscripts and submit their opinions. Editors can manage the whole submission/review/revise/publish process.

Manuscripts number will be provided to the corresponding author within 72 hours for the respective manuscript submitted.

With best Regards,

Grace

Journal Manager

Journal of Ecosystem and Ecography

Whatsup: +44-20-3608-4181